Hyperemesis Gravidarum Genetic Breakthrough


I’m a two time Hyperemesis Gravidarum survivor and supporter of the Her Foundation. Sharing the newest genetic’s study from the Her Foundation and I quote, “This study provides scientific evidence linking 2 genes, GDF15 and IGFBP7, to HG. These genes provide the instructions to build the proteins GDF15 and IGFBP7 in the human placenta during pregnancy. The proteins are known to be important in the development of the placenta and in controlling appetite. We have done additional work presented at the ICHG showing that not only are these genes linked to HG, but also, the proteins are abnormally high in the blood from patients hospitalized with HG.

This suggests that the DNA instructions in some HG patients are telling the placenta to make too much GDF15 and IGFBP7 protein, which then gets into the mother’s blood, and causes extreme nausea and vomiting. This information provides strong evidence that these proteins are directly involved in causing HG. It puts an end to the unfortunate misogynistic nonsense that HG is “all in your head.

Thank you for reading and if you’re interested in more information on HG read my earlier post here The Truth About Hyperemesis Gravidarum

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